Pharmaceutical Cone Mills
NINGRUI supplies cone mills for pharmaceutical wet and dry sizing duties. The equipment reduces oversized agglomerates as material moves through an impeller and conical screen assembly.
Set the Sizing Duty Before Choosing the Screen
Feed, Impeller, and Screen
Wet mass and dried granules behave differently during milling. Feed moisture, initial lump size, and material sensitivity influence the screen and impeller selection. Screen aperture alone does not define the finished particle-size distribution.
Product Recovery and Access
Review the feed and discharge arrangement, contact-part access, and cleaning method. The target is the required size distribution at a suitable processing rate; excessive fines and heat generation need to be considered during process trials.
Technical Specification Basis
| Item | Requirement to Define |
|---|---|
| Feed material | Wet/dry condition, lump size, moisture, density, and sensitivity |
| Sizing target | Particle-size distribution and acceptable fines |
| Milling configuration | Screen design, impeller, speed range, and feed arrangement |
| Process duty | Batch mass, required rate, and product test conditions |
| Interfaces | Inlet/outlet, receiving vessel, cleaning, and dust-control connections |
The selected model's capacity and operating range require confirmation against the material and configuration.
Applications Within Wet Granulation
A wet sizing step can break up the mass discharged from a high-shear granulator before drying. Dry sizing can address agglomerates after drying and before final blending. Each duty needs its own feed specification and sizing target.
Coordinate the Granulation Sequence
See high-shear granulators for wet mass formation and bin blenders for subsequent dry blending. Specify which sizing step the cone mill will serve.
Request a Cone Mill Selection
Send representative feed properties, the required size distribution, batch mass, and process location. Include available trial data and the proposed upstream and downstream connections.
Send a Cone Mill Inquiry